Subject:  Radiation and cancer cells.....
Date:     Sun, 12 Jul 1998 224729 -0500 (CDT)
From:     "Roy L. Beavers" <rbeavers@llion.org>
To:       emfguru@hotmail.com
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Scientists Discover the Means by Which Cancer Cells Recover from Exposure to
Radiation

ST. PAUL, Minn., July 8 /PRNewswire/ -- A study published July 10 in the
Journal of Biological Chemistry, official journal of the American Society for
Biochemistry and Molecular Biology, demonstrates the means by which cells
recover from exposure to radiation.  This research shows that a novel drug
developed by Hughes Institute researchers shows promise as a means to making
cells more sensitive to radiation.

There is currently a need for therapeutic agents and methods that are useful
for preventing or reducing cell damage that results from exposure to radiation
and chemical agents that cause DNA-damage.

This compound may also be useful for treating conditions that result from
exposure to radiation or to chemical agents that cause DNA damage.  Conditions
that result from exposure to DNA-damaging agents include conditions that
result from oxidative stress, such as tissue or organ damage, inflammation,
and hair loss, as well as the negative effects that are produced by oxygen
free radicals during chemotherapy.  Oxidative stress may result from exposure
to external agents, or may result from internal processes.  Thus, these
inhibitors are also useful for treating conditions resulting from the action
of internally generated oxygen free radicals, such as aging and amyelotrophic
lateral sclerosis (ALS).

Reference:  Goodman PA, Niehoff LB, Uckun FM.  Role of tyrosine kinases in
induction of c-jun protooncogene in irradiated B-lineage lymphoid cells.
Journal of Biological Chemistry, 273:17742-17748, 1998.

SOURCE  Hughes Institute





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Reprinted with permission of Roy Beavers, http://www.feb.se/EMF-L/EMF-L.html