Subject:  Re Oxygen, EMF's and Health...(fwd)
Date:     Wed, 27 May 1998 110646 -0500 (CDT)
From:     "Roy L. Beavers" <rbeavers@llion.org>
To:       emfguru@hotmail.com
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---------- Forwarded message ----------
Date: Wed, 27 May 1998 11:26:15 EDT
From: Cogreslab 
To: rbeavers@llion.org
Subject: Re: Oxygen, EMF's and Health...(fwd)

Dear Roy, 

The probable mechanism of interaction between weak electric fields and oxygen
takes place at the inner mitochondrial membrane where ATP (adenosine
triphosphate) is synthesised. ATP prorovides 90 percent of organic cellular
energy. ATP is synthesised by a system of electron transport which relies on a
220mV potential difference across the inner mitochondrial matrix space.
Electrons surplus to this process are accepted by molecular oxygen (a kind of
electron dustbin) which is the final electron acceptor in oxidative
phosphorylation. Electric fields have been shown to depolarise this membrane,
causing havoc with ATP synthesis. This therefore shows up in a wide variety of
bioeffects, such as reduced lymphocyte competence, chronic fatigue, muscular
pain, etc. for example.

In these exposure conditions organic cells seek alternative pathways for ATP
synthesis, turning to a more primitive means known as glycolysis (the Embden
Mayerhoff pathway). This pathway requires three times as much glucose, so
cells start resorbing their plasma membrane glycoproteins or synthesising less
of them. The trouble is that plasma membrane glycoproteins are the unique
means of signal transduction into the cellular interior. So their absence
(noted on most cancer cells) causes cells to proliferate out of regulatory
control, increasing the chances of their becomming aberrant. That this
mechanims is correct was demonstrated by Goldstein and Cameron in 1952, when
they were able to make normal cells turn cancerous simply by starving them of
oxygen. At a human studies level we showed in 1996 that ME is doubled in homes
where the bedplace E-fields are elevated above about 15V/m(normally only about
5Vm). 

Of course there is also a role for free radicals in carcinogenesis, but such
can be genrated from other means than EM field exposure, and normally there
are several antioxidants ready to mop up such spillages.

I hope that a careful reading of the above may help understanding.

Best Wishes, 

Roger Coghill



Archive provided courtesy of WaveGuide, http://www.wave-guide.org
Reprinted with permission of Roy Beavers, http://www.feb.se/EMF-L/EMF-L.html