Subject:  (Sobel) Alzheimer's Disease, contributing factor.... (fwd)
Date:     Fri, 23 Oct 1998 101405 -0500 (CDT)
From:     "Roy L. Beavers" <rbeavers@llion.org>
To:       emfguru <rbeavers@llion.org>
--------------------------------------------------


.......Dr. Sobel is perhaps the number one authority on this subject....
....guru.....

---------- Forwarded message ----------
Date: Fri, 23 Oct 1998 10:45:17 EDT
From: SobelHERI@xxxxxxx
To: rbeavers@llion.org
Subject: Re: Alzheimer's Disease, contributing factor....

Roy:

It is my guess that EMF does not directly affect neurons.  We have two
complementary hypothesis - one published in our 1996 hypothesis paper in
Neurology which you have from the San Antonio meeting - and one related to
melatonin down-regulation.  We hypothesized that EMF exposure may cause
increased production of amyloid beta peripherally, e.g., by skin cells, which
then migrates to the brain and over the years accumulates sufficiently to
aggregate and become neurotoxic, etc. etc.  As you are well aware, melatonin
production can apparently be decreased by EMF exposure.  Melatonin is
apparently capable of reducing oxidative damage to neurons and inhibiting the
neurotoxicity of amyloid beta - in laboratory cellular studies.  Thus, EMF
exposure may concurrently product 2 affects leading to Alzheimer's disease
initiation and progression.  Once the process is started in the brain, it is
self-perpetuating.  We think that decades of EMF exposure are likely required.

We have submitted a proposal to a funding governmental agency to
partiallly test these theories by investigating amyloid beta and melatonin
production in workers in specific occupations.

We shall see what happens.

Gene Sobel

I hope all is well with you.



Archive provided courtesy of WaveGuide, http://www.wave-guide.org
Reprinted with permission of Roy Beavers, http://www.feb.se/EMF-L/EMF-L.html