Subject: Another analysis of childhood leukemia studies (Bowman).
Date: Mon, 16 Oct 2000 172833 -0500
From: Roy Beavers
To: guru
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............From EMF-L..........
I realize that these results were not written for the likes of us...... Science often
feels
the need to "encrypt" its work so that "ordinary people" (college level) won't
understand what they are saying...... It makes 'em feel big.......
Anyway, don't fret -- I'm sure that Joe will oblige us with a translation soon......
(It does not appear to me that the reusults represent anything really new......)
Cheerio...........guru.........
-------- Original Message --------
Subject: Pooled analysis of childhood leukemia studies by Greenland et al.
Date: Mon, 16 Oct 2000 16:20:32 -0400
From: "Bowman, Joseph D."
To: "'roy@emfguru.com'"
A POOLED ANALYSIS OF MAGNETIC FIELDS, WIRE CODES, AND CHILDHOOD LEUKEMIA
S. Greenland1, A. R. Sheppard2, W. T. Kaune3, C. Poole4, M.A. Kelsh5, for the Childhood
Leukemia-EMF Study Group*
Epidemiology, October 2000, Volume 11, Number 6
Abstract. We obtained original individual data from 15 studies of magnetic fields or wire
codes and childhood leukemia, and estimated magnetic-field exposure for subjects with
sufficient data to do so. Summary estimates from 12 studies that supplied magnetic-field
measures exhibited little or no association of magnetic fields with leukemia when
comparing 0.1-0.2 and 0.2-0.3 microtesla (mT) categories to the 0-0.1 m T category, but
the Mantel-Haenszel summary odds ratio comparing >0.3 m T to 0-0.1 mT was 1.7 (95%
confidence limits (CL) = 1.2-2.3). Similar results were obtained using covariate
adjustment and spline regression. The study-specific relations appeared consistent despite
the numerous methodologic differences among the studies. The association of wire codes
with leukemia varied considerably across studies, with odds-ratio estimates for very-high
current versus low-current configurations ranging from 0.7 to 3.0 (homogeneity P = 0.005).
Based on a survey of household magnetic fields, an estimate of the U.S. population
attributable fraction of childhood leukemia associated with residential exposure is 3%
(95% CL = -2%, 8%). Our results contradict the idea that the magnetic-field association
with leukemia is less consistent than the wire-code association with leukemia, although
analysis of the 4 studies with both measures indicates that the wire-code association is
not explained by measured fields. The results also suggest that appreciable magnetic-field
effects, if any, may be concentrated among relatively high and uncommon exposures, and
that studies of highly exposed populations would be needed to clarify the relation of
magnetic fields to childhood leukemia.
1Department of Epidemiology, UCLA School of Public Health
2Asher Sheppard Consulting and Department of Physiology, Loma Linda University, Loma Linda
CA
3EM Factors, Richland, WA
4Department of Epidemiology, University of North Carolina School of Public Health, Chapel
Hill, NC
5Exponent Health Group, Menlo Park, CA
* The Childhood Leukemia-EMF Study Group consists of:
Data Contributors: A. Ahlbom and M. Feychting (Karolinska Institute), R. Coghill (Coghill
Research Laboratories), EPRI (magnetic-field survey data), J. Dockerty (U. of Otago), A.
Fajardo-Gutiérrez (Centro Médico Nacional Siglo XXI), J. Fulton (Rhode Island Department
of Health), M. Koskenvuo (U. of Turku), M. Linet (National Cancer Institute), S. London
(National Institute of Environmental Health Science), M. McBride (British Columbia Cancer
Agency), J. Michaelis (Johannes Gutenberg-University of Mainz), J. Olsen (Danish Cancer
Society), J. Peters (U. of Southern California), E. Pukkala (Finnish Cancer Registry), D.
Savitz (U. of North Carolina), J. Schüz (Johannes Gutenberg-University of Mainz), L.
Tomenius, T. Tynes (Norwegian Radiation Protection Authority), P. Verkasalo (U. of
Helsinki), N. Wertheimer (U. of Colorado).
Scientific Reviewers: A. Ahlbom, K. Ebi (EPRI), A. Fajardo-Gutiérrez, M. Feychting, L.
Kheifets (EPRI), R. Neutra (California Department of Health Services), J. Robins (Harvard
U.), D. Savitz, J. Schüz, P. Verkasalo, N. Wertheimer.
Pooled Database Assembly: R. Mrad, B. Smith, K. Zhao (Exponent Health Group); M. Atherton
(EcoAnalysis, Inc.).
Acknowledgments: We thank Jack Sahl for scientific contributions at the inception of this
project and the referees for their criticisms. This research supported by grant number R03
ES-08920 from the National Institute of Environmental Health Sciences (NIEHS). Southern
California Edison Co. supported previous work that contributed to this report.
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Content-Type: text/html; charset=us-ascii
Content-Transfer-Encoding: 7bit
............From EMF-L..........
I realize that these results were not written for the likes of us......
Science often feels
the need to "encrypt" its work so that "ordinary people" (college level)
won't
understand what they are saying...... It makes 'em feel big.......
Anyway, don't fret -- I'm sure that Joe will oblige us with a translation
soon......
(It does not appear to me that the reusults represent anything really
new......)
Cheerio...........guru.........
-------- Original Message --------
| Subject: |
Pooled analysis of childhood leukemia studies by Greenland et al. |
| Date: |
Mon, 16 Oct 2000 16:20:32 -0400 |
| From: |
"Bowman, Joseph D." <jdb0@cdc.gov> |
| To: |
"'roy@emfguru.com'" <roy@emfguru.com> |
A POOLED ANALYSIS OF MAGNETIC FIELDS, WIRE CODES, AND CHILDHOOD LEUKEMIA
S. Greenland1, A. R. Sheppard2, W. T. Kaune3,
C. Poole4, M.A. Kelsh5, for the Childhood Leukemia-EMF
Study Group*
Epidemiology,
October 2000, Volume 11, Number 6
Abstract. We obtained original individual data from 15 studies
of magnetic fields or wire codes and childhood leukemia, and estimated
magnetic-field exposure for subjects with sufficient data to do so. Summary
estimates from 12 studies that supplied magnetic-field measures exhibited
little or no association of magnetic fields with leukemia when comparing
0.1-0.2 and 0.2-0.3 microtesla (mT) categories
to the 0-0.1 m T category, but the Mantel-Haenszel
summary odds ratio comparing >0.3 m T to 0-0.1
mT was 1.7 (95% confidence limits (CL) = 1.2-2.3).
Similar results were obtained using covariate adjustment and spline regression.
The study-specific relations appeared consistent despite the numerous methodologic
differences among the studies. The association of wire codes with leukemia
varied considerably across studies, with odds-ratio estimates for very-high
current versus low-current configurations ranging from 0.7 to 3.0 (homogeneity
P = 0.005). Based on a survey of household magnetic fields, an estimate
of the U.S. population attributable fraction of childhood leukemia associated
with residential exposure is 3% (95% CL = -2%, 8%). Our results contradict
the idea that the magnetic-field association with leukemia is less consistent
than the wire-code association with leukemia, although analysis of the
4 studies with both measures indicates that the wire-code association is
not explained by measured fields. The results also suggest that appreciable
magnetic-field effects, if any, may be concentrated among relatively high
and uncommon exposures, and that studies of highly exposed populations
would be needed to clarify the relation of magnetic fields to childhood
leukemia.
1Department
of Epidemiology, UCLA School of Public Health
2Asher
Sheppard Consulting and Department of Physiology, Loma Linda University,
Loma Linda CA
3EM
Factors, Richland, WA
4Department
of Epidemiology, University of North Carolina School of Public Health,
Chapel Hill, NC
5Exponent
Health Group, Menlo Park, CA
* The Childhood
Leukemia-EMF Study Group consists of:
Data Contributors:
A. Ahlbom and M. Feychting (Karolinska Institute), R. Coghill (Coghill
Research Laboratories), EPRI (magnetic-field survey data), J. Dockerty
(U. of Otago), A. Fajardo-Gutiérrez (Centro Médico Nacional
Siglo XXI), J. Fulton (Rhode Island Department of Health), M. Koskenvuo
(U. of Turku), M. Linet (National Cancer Institute), S. London (National
Institute of Environmental Health Science), M. McBride (British Columbia
Cancer Agency), J. Michaelis (Johannes Gutenberg-University of Mainz),
J. Olsen (Danish Cancer Society), J. Peters (U. of Southern California),
E. Pukkala (Finnish Cancer Registry), D. Savitz (U. of North Carolina),
J. Schüz (Johannes Gutenberg-University of Mainz), L. Tomenius, T.
Tynes (Norwegian Radiation Protection Authority), P. Verkasalo (U. of Helsinki),
N. Wertheimer (U. of Colorado).
Scientific Reviewers:
A. Ahlbom, K. Ebi (EPRI), A. Fajardo-Gutiérrez, M. Feychting, L.
Kheifets (EPRI), R. Neutra (California Department of Health Services),
J. Robins (Harvard U.), D. Savitz, J. Schüz, P. Verkasalo, N. Wertheimer.
Pooled Database
Assembly: R. Mrad, B. Smith, K. Zhao (Exponent Health Group); M. Atherton
(EcoAnalysis, Inc.).
Acknowledgments:
We thank Jack Sahl for scientific contributions at the inception of this
project and the referees for their criticisms. This research supported
by grant number R03 ES-08920 from the National Institute of Environmental
Health Sciences (NIEHS). Southern California Edison Co. supported previous
work that contributed to this report.
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Archive provided courtesy of WaveGuide, http://www.wave-guide.org
Reprinted with permission of Roy Beavers, http://www.emfguru.com